Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Differential gene expression of young and senescent HUVECs under static and laminar shear stress conditions

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA110385 | ENA |

REPOSITORIES: ENA

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Publications

Differential gene expression in young and senescent endothelial cells under static and laminar shear stress conditions.

Mun Gyeong In GI   Lee Seung Jin SJ   An Sang Mi SM   Kim In Kyeom IK   Boo Yong Chool YC  

Free radical biology & medicine 20090503 3


Laminar shear stress (LSS) caused by blood flow is known to regulate endothelial function and to contribute to vascular health. By way of contrast, endothelial cell senescence seems to increase the incidence of vascular disorders. In an attempt to identify genes associated with vascular health/disease states, this study assessed the differential gene expression of young and senescent human umbilical vein endothelial cells (HUVECs) under static and LSS conditions. Replicative cell senescence was  ...[more]

Publication: 1/2

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