Genomics

Dataset Information

0

Legionella pneumophila


ABSTRACT: Gene expression profiling of constitutively competent comR and proQ mutants and RNase R (rnr) mutant of L. pneumophila

ORGANISM(S): Legionella pneumophila  

PROVIDER: PRJNA110987 | ENA |

REPOSITORIES: ENA

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Publications

Loss of RNase R induces competence development in Legionella pneumophila.

Charpentier Xavier X   Faucher Sébastien P SP   Kalachikov Sergey S   Shuman Howard A HA  

Journal of bacteriology 20081010 24


RNase R is a processive 3'-5' exoribonuclease with a high degree of conservation in prokaryotes. Although some bacteria possess additional hydrolytic 3'-5' exoribonucleases such as RNase II, RNase R was found to be the only predicted one in the facultative intracellular pathogen Legionella pneumophila. This provided a unique opportunity to study the role of RNase R in the absence of an additional RNase with similar enzymatic activity. We investigated the role of RNase R in the biology of Legione  ...[more]

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