Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Genome-wide analysis of expression and DNA methylation at CpG-island-associated sense-antisense transcript loci in mouse

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA111365 | ENA |

REPOSITORIES: ENA

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Publications

Genome-wide analysis of expression modes and DNA methylation status at sense-antisense transcript loci in mouse.

Watanabe Yutaka Y   Numata Koji K   Murata Shinya S   Osada Yuko Y   Saito Rintaro R   Nakaoka Hajime H   Yamamoto Naoyuki N   Watanabe Kazufumi K   Kato Hidemasa H   Abe Kuniya K   Kiyosawa Hidenori H  

Genomics 20100822 6


The functionality of sense-antisense transcripts (SATs), although widespread throughout the mammalian genome, is largely unknown. Here, we analyzed the SATs expression and its associated promoter DNA methylation status by surveying 12 tissues of mice to gain insights into the relationship between expression and DNA methylation of SATs. We have found that sense and antisense expression positively correlate in most tissues. However, in some SATs with tissue-specific expression, the expression leve  ...[more]

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