Project description:Comparisons among breast cancer metastases at different organs revealed distinct microenvironments as characterized by cytokine content. Such microenvironment distinction might be important to dictate how the cancer cells adapt to survival before they successfully colonize. This SuperSeries is composed of the following subset Series:; GSE14017: Metastases of breast cancer (U133plus2); GSE14018: Metastases of breast cancer (U133A) Experiment Overall Design: Refer to individual Series
Project description:Comparisons among breast cancer metastases at different organs revealed distinct microenvironments as characterized by cytokine content. Such microenvironment distinction might be important to dictate how the cancer cells adapt to survival before they successfully colonize. Experiment Overall Design: 58 breast cancer metastases from different organs were profiled and compared by the expression level of over 400 cytokines. 36 samples were incuded in this series. 22 others as well as 7 of these 36 were profiled on U133plus2 platforms and included in series GSE14017.