Genomics

Dataset Information

0

Saccharomyces cerevisiae


ABSTRACT: GRO analysis of rap1-sil, tpk1 & tpk2.

ORGANISM(S): Saccharomyces cerevisiae  

PROVIDER: PRJNA114627 | ENA |

REPOSITORIES: ENA

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Publications

Regulon-specific control of transcription elongation across the yeast genome.

Pelechano Vicent V   Jimeno-González Silvia S   Rodríguez-Gil Alfonso A   García-Martínez José J   Pérez-Ortín José E JE   Chávez Sebastián S  

PLoS genetics 20090821 8


Transcription elongation by RNA polymerase II was often considered an invariant non-regulated process. However, genome-wide studies have shown that transcriptional pausing during elongation is a frequent phenomenon in tightly-regulated metazoan genes. Using a combination of ChIP-on-chip and genomic run-on approaches, we found that the proportion of transcriptionally active RNA polymerase II (active versus total) present throughout the yeast genome is characteristic of some functional gene classe  ...[more]

Publication: 1/2

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