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Using high-density exon arrays to profile gene expression in closely related species

ABSTRACT: Using high-density exon arrays to profile gene expression in closely related species

PROVIDER: PRJNA115613 | ENA |

REPOSITORIES: ENA

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Using high-density exon arrays to profile gene expression in closely related species

Project description:This SuperSeries is composed of the following subset Series: GSE15626: Using high-density exon arrays to profile gene expression in closely related species (Exon 1.0 ST) GSE15665: Using high-density exon arrays to profile gene expression in closely related species (HJAY) Refer to individual Series

2009-05-04 | E-GEOD-15666 | biostudies-arrayexpress

Using high-density exon arrays to profile gene expression in closely related species (Exon 1.0 ST)

Project description:Global comparisons of gene expression profiles between species provide significant insight into gene regulation, evolutionary processes, and disease mechanisms. In this work, we describe a flexible and intuitive approach for global expression profiling of closely related species, using high-density exon arrays designed for a single reference genome. The high-density probe coverage of exon arrays allows us to select the identical set of perfect-match probes for measuring expression levels of orthologous genes. This eliminates a serious confounding factor in probe affinity effects of species-specific microarray probes, and enables direct comparisons of estimated expression indexes across species. Keywords: analysis of gene expression in tissues

2009-05-05 | GSE15626 | GEO

Using high-density exon arrays to profile gene expression in closely related species (HJAY)

2009-05-05 | GSE15665 | GEO

Using high-density exon arrays to profile gene expression in closely related species (Exon 1.0 ST)

2009-05-04 | E-GEOD-15626 | biostudies-arrayexpress

Using high-density exon arrays to profile gene expression in closely related species (HJAY)

2010-05-19 | E-GEOD-15665 | biostudies-arrayexpress

Using high-density exon arrays to profile gene expression in closely related species (HJAY)

Project description:Using high-density exon arrays to profile gene expression in closely related species (HJAY)

| PRJNA122927 | ENA

Using high-density exon arrays to profile gene expression in closely related species

Project description:This SuperSeries is composed of the SubSeries listed below.

2009-05-05 | GSE15666 | GEO

Using high-density exon arrays to profile gene expression in closely related species.

Project description: Not available

| S-EPMC2709591 | biostudies-literature

High-density spatial transcriptomics arrays for in situ tissue profiling

Project description:High-density spatial transcriptomics arrays for in situ tissue profiling

| PRJNA540976 | ENA

A Systematic Comparison and Evaluation of High Density Exon Arrays and RNA-seq technology in Unraveling the Peripheral Blood Transcriptome of Sickle Cell Disease.

Project description:Sickle cell transcriptome was analyzed using whole blood clinical specimens on the Affymetrix Human Exon 1.0 ST arrays and Illumina’s deep sequencing technologies. Data analysis indicated a strong concordance (R=0.64) between exon array and RNA-seq in both gene level and exon level expression of transcripts. The magnitude of fold changes in the expression levels for the differentially expressed genes (p<0.05) was found to be higher in RNA-seq than microarrays. However, the arrays outperformed the sequencing technology in the detection of low abundant transcripts. In addition to examining the expression level changes of transcripts, RNA-seq technology was able to identify sequence variation in the expressed transcripts. We also demonstrate herein the ability of RNA-seq technology to discover novel expression outside of the annotated genes.

2012-07-06 | GSE31757 | GEO

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