Dataset Information


Escherichia coli str. K-12 substr. MG1655

ABSTRACT: Transcriptome analysis of E.coli MG1655 under multiple growth conditions

ORGANISM(S): Escherichia coli str. K-12 substr. MG1655  



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The transcription unit architecture of the Escherichia coli genome.

Cho Byung-Kwan BK   Zengler Karsten K   Qiu Yu Y   Park Young Seoub YS   Knight Eric M EM   Barrett Christian L CL   Gao Yuan Y   Palsson Bernhard Ø BØ  

Nature biotechnology 20091101 11

Bacterial genomes are organized by structural and functional elements, including promoters, transcription start and termination sites, open reading frames, regulatory noncoding regions, untranslated regions and transcription units. Here, we iteratively integrate high-throughput, genome-wide measurements of RNA polymerase binding locations and mRNA transcript abundance, 5' sequences and translation into proteins to determine the organizational structure of the Escherichia coli K-12 MG1655 genome.  ...[more]

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