Dataset Information


Mus musculus

ABSTRACT: Host lung gene expression patterns predict the etiology of infectious pneumonias

ORGANISM(S): Mus musculus  



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Host lung gene expression patterns predict infectious etiology in a mouse model of pneumonia.

Evans Scott E SE   Tuvim Michael J MJ   Zhang Jiexin J   Larson Derek T DT   García Cesar D CD   Martinez-Pro Sylvia S   Coombes Kevin R KR   Dickey Burton F BF  

Respiratory research 20100723

Lower respiratory tract infections continue to exact unacceptable worldwide mortality, often because the infecting pathogen cannot be identified. The respiratory epithelia provide protection from pneumonias through organism-specific generation of antimicrobial products, offering potential insight into the identity of infecting pathogens. This study assesses the capacity of the host gene expression response to infection to predict the presence and identity of lower respiratory pathogens without r  ...[more]

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