Dataset Information


Rattus norvegicus

ABSTRACT: Differentially expressed genes after treatment with hydroxytyrosol in DMBA-induced rat breast tumors

ORGANISM(S): Rattus norvegicus  



altmetric image


Hydroxytyrosol inhibits growth and cell proliferation and promotes high expression of sfrp4 in rat mammary tumours.

Granados-Principal Sergio S   Quiles Jose L JL   Ramirez-Tortosa Cesar C   Camacho-Corencia Pedro P   Sanchez-Rovira Pedro P   Vera-Ramirez Laura L   Ramirez-Tortosa M Carmen MC  

Molecular nutrition & food research 20101201

SCOPE: Hydroxytyrosol (a phenolic compound derived from virgin olive oil) has demonstrated an anti-tumour effect in several tumour cell lines in addition to other health-related properties. The aim of this study was to investigate, for the first time in an animal model of experimental mammary carcinoma, the anti-cancer ability of hydroxytyrosol and to discover which pathways are modified by hydroxytyrosol. METHODS AND RESULTS: Dimethylbenz[α]anthracene-induced mammary tumours were induced in 28  ...[more]

Similar Datasets

| PRJNA115165 | ENA
| PRJNA115167 | ENA
2016-03-07 | E-MTAB-4552 | ArrayExpress
2008-10-28 | GSE13356 | GEO
2009-09-30 | GSE15223 | GEO
| PRJNA118109 | ENA
2008-10-28 | E-GEOD-13356 | ArrayExpress
| PRJNA102593 | ENA
| GSE89462 | GEO
2009-09-30 | GSE15243 | GEO