Genomics

Dataset Information

27

Escherichia coli


ABSTRACT: Global transcriptome response of recombinant E. coli to heat-shock and dual heat-shock recombinant protein induction

ORGANISM(S): Escherichia coli  

PROVIDER: PRJNA118773 | ENA |

REPOSITORIES: ENA

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Publications

Global transcriptome response of recombinant Escherichia coli to heat-shock and dual heat-shock recombinant protein induction.

Harcum Sarah W SW   Haddadin Fu'ad T FT  

Journal of industrial microbiology & biotechnology 20060506 10


Recombinant Escherichia coli cultures are used to manufacture numerous therapeutic proteins and industrial enzymes, where many of these processes use elevated temperatures to induce recombinant protein production. The heat-shock response in wild-type E. coli has been well studied. In this study, the transcriptome profiles of recombinant E. coli subjected to a heat-shock and to a dual heat-shock recombinant protein induction were examined. Most classical heat-shock protein genes were identified a  ...[more]

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