Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Global gene expression analysis of (1) chemically reprogrammed iPS cells, and (2) chemical-treated cells

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA119647 | ENA |

REPOSITORIES: ENA

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Publications


The combined activity of three transcription factors can reprogram adult cells into induced pluripotent stem cells (iPSCs). However, the transgenic methods used for delivering reprogramming factors have raised concerns regarding the future utility of the resulting stem cells. These uncertainties could be overcome if each transgenic factor were replaced with a small molecule that either directly activated its expression from the somatic genome or in some way compensated for its activity. To this  ...[more]

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