Dataset Information


Pimephales promelas

ABSTRACT: Effects of pulp and paper mill effluents on gene expression in the fathead minnow hypothalamus

ORGANISM(S): Pimephales promelas  



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Gene expression profiling of the fathead minnow (Pimephales promelas) neuroendocrine brain in response to pulp and paper mill effluents.

Popesku Jason T JT   Tan Elvin Y Z EY   Martel Pierre H PH   Kovacs Tibor G TG   Rowan-Carroll Andrea A   Williams Andrew A   Yauk Carole C   Yauk Carole C   Trudeau Vance L VL  

Aquatic toxicology (Amsterdam, Netherlands) 20100604 3

The toxicity of pulp and paper mill effluents (PPMEs) has been greatly decreased, yet some continue to negatively affect fish reproduction. We hypothesized that PPMEs are affecting the brain resulting in decreased reproductive performance. Our goal was to use gene expression profiling to test the hypothesis that PPMEs are having an effect on neural systems in the fathead minnow (FHM; Pimephales promelas) in vivo. Sexually mature male and female FHM were exposed to 100% final biotreated PPMEs fro  ...[more]

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