Genomics

Dataset Information

0

Escherichia coli str. K-12 substr. W3110


ABSTRACT: High succinic acid tolerance E.coli (DST160)

ORGANISM(S): Escherichia coli str. K-12 substr. W3110  

PROVIDER: PRJNA120029 | ENA |

REPOSITORIES: ENA

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Publications

Long-term continuous adaptation of Escherichia coli to high succinate stress and transcriptome analysis of the tolerant strain.

Kwon Yeong-Deok YD   Kim Susie S   Lee Sang Yup SY   Kim Pil P  

Journal of bioscience and bioengineering 20100909 1


To understand the responses of Escherichia coli to high succinate stress and to determine the roles of upregulated genes in high succinate tolerance, a continuous culture of wild-type E. coli W3110 was performed for 268 days in a gradually increasing concentration of succinate. Growth of the final adapted strain, designated DST160, proceeded growth rate of 0.20 h(-1) without a lag phase in medium containing 0.592 M succinate, while the wild-type strain showed 0.02 h(-1) in 38 h. The growth rates  ...[more]

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