Dataset Information


Homo sapiens

ABSTRACT: Analyses of heterogeneous renal allograft biopsies reveal conserved rejection signatures and molecular pathways I, partB

ORGANISM(S): Homo sapiens  



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Analysis of independent microarray datasets of renal biopsies identifies a robust transcript signature of acute allograft rejection.

Saint-Mezard Pierre P   Berthier Céline C CC   Zhang Hai H   Hertig Alexandre A   Kaiser Sergio S   Schumacher Martin M   Wieczorek Grazyna G   Bigaud Marc M   Kehren Jeanne J   Rondeau Eric E   Raulf Friedrich F   Marti Hans-Peter HP  

Transplant international : official journal of the European Society for Organ Transplantation 20081106 3

Transcriptomics could contribute significantly to the early and specific diagnosis of rejection episodes by defining 'molecular Banff' signatures. Recently, the description of pathogenesis-based transcript sets offered a new opportunity for objective and quantitative diagnosis. Generating high-quality transcript panels is thus critical to define high-performance diagnostic classifier. In this study, a comparative analysis was performed across four different microarray datasets of heterogeneous s  ...[more]

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