Genomics

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ABSTRACT: A gene signature predictive for outcome in advanced ovarian cancer identifies a novel survival factor: MAGP2

PROVIDER: PRJNA120193 | ENA |

REPOSITORIES: ENA

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Publications


Advanced stage papillary serous tumors of the ovary are responsible for the majority of ovarian cancer deaths, yet the molecular determinants modulating patient survival are poorly characterized. Here, we identify and validate a prognostic gene expression signature correlating with survival in a series of microdissected serous ovarian tumors. Independent evaluation confirmed the association of a prognostic gene microfibril-associated glycoprotein 2 (MAGP2) with poor prognosis, whereas in vitro m  ...[more]

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