Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Apoptosis regulation by Kaposi’s sarcoma microRNAs

PROVIDER: PRJNA120977 | ENA |

REPOSITORIES: ENA

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Publications


Kaposi's sarcoma herpesvirus (KSHV) encodes a cluster of twelve micro (mi)RNAs, which are abundantly expressed during both latent and lytic infection. Previous studies reported that KSHV is able to inhibit apoptosis during latent infection; we thus tested the involvement of viral miRNAs in this process. We found that both HEK293 epithelial cells and DG75 cells stably expressing KSHV miRNAs were protected from apoptosis. Potential cellular targets that were significantly down-regulated upon KSHV  ...[more]

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