Dataset Information


Homo sapiens

ABSTRACT: Transcriptome Analysis and Molecular Signature of Human Retinal Pigment Epithelium

ORGANISM(S): Homo sapiens  



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Transcriptome analysis and molecular signature of human retinal pigment epithelium.

Strunnikova N V NV   Maminishkis A A   Barb J J JJ   Wang F F   Zhi C C   Sergeev Y Y   Chen W W   Edwards A O AO   Stambolian D D   Abecasis G G   Swaroop A A   Munson P J PJ   Miller S S SS  

Human molecular genetics 20100401 12

Retinal pigment epithelium (RPE) is a polarized cell layer critical for photoreceptor function and survival. The unique physiology and relationship to the photoreceptors make the RPE a critical determinant of human vision. Therefore, we performed a global expression profiling of native and cultured human fetal and adult RPE and determined a set of highly expressed 'signature' genes by comparing the observed RPE gene profiles to the Novartis expression database (SymAtlas:  ...[more]

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