Genomics

Dataset Information

0

Danio rerio


ABSTRACT: Experiment 4: Affymetrix validation array

ORGANISM(S): Danio rerio  

PROVIDER: PRJNA123377 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

Pou5f1 contributes to dorsoventral patterning by positive regulation of vox and modulation of fgf8a expression.

Belting Heinz-Georg HG   Wendik Björn B   Lunde Karen K   Leichsenring Manuel M   Mössner Rebecca R   Driever Wolfgang W   Onichtchouk Daria D  

Developmental biology 20110520 2


Pou5f1/Oct-4 in mice is required for maintenance of embryonic pluripotent cell populations. Zebrafish pou5f1 maternal-zygotic mutant embryos (spiel ohne grenzen; MZspg) lack endoderm and have gastrulation and dorsoventral patterning defects. A contribution of Pou5f1 to the control of bmp2b, bmp4 and vox expression has been suggested, however the mechanisms remained unclear and are investigated in detail here. Low-level overexpression of a Pou5f1-VP16 activator fusion protein can rescue dorsaliza  ...[more]

Publication: 1/2

Similar Datasets

| PRJNA123447 | ENA
| PRJNA123449 | ENA
| PRJNA123455 | ENA
| PRJNA123445 | ENA
2010-03-07 | E-GEOD-17657 | ArrayExpress
| PRJNA123375 | ENA
| PRJNA101317 | ENA
| PRJNA95495 | ENA
| PRJNA175818 | ENA
| PRJNA123373 | ENA