Dataset Information


Mus musculus

ABSTRACT: Gene expression profiles of renin producing cells in newborn and adult kidney isolated from Renin-YFP transgenic mice using FACS. (GUDMAP Series ID: 29)

ORGANISM(S): Mus musculus  



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Defining the molecular character of the developing and adult kidney podocyte.

Brunskill Eric W EW   Georgas Kylie K   Rumballe Bree B   Little Melissa H MH   Potter S Steven SS  

PloS one 20110908 9

The podocyte is a remarkable cell type, which encases the capillaries of the kidney glomerulus. Although mesodermal in origin it sends out axonal like projections that wrap around the capillaries. These extend yet finer projections, the foot processes, which interdigitate, leaving between them the slit diaphragms, through which the glomerular filtrate must pass. The podocytes are a subject of keen interest because of their key roles in kidney development and disease.In this report we identified  ...[more]

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