Genomics

Dataset Information

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Drosophila melanogaster


ABSTRACT: Chronic activation of the epithelial immune system of the fruit fly's salivary glands has a negative effect on organismal growth and induces a peculiar set of target genes

PROVIDER: PRJNA124385 | ENA |

REPOSITORIES: ENA

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Chronic activation of the epithelial immune system of the fruit fly's salivary glands has a negative effect on organismal growth and induces a peculiar set of target genes.

Abdelsadik Ahmed A   Roeder Thomas T  

BMC genomics 20100426


<h4>Background</h4>Epithelial and especially mucosal immunity represents the first line of defence against the plethora of potential pathogens trying to invade via the gastrointestinal tract. The salivary glands of the fruit fly are an indispensable part of the gastrointestinal tract, but their contribution to the mucosal immunity has almost completely been neglected. Our major goal was to elucidate if the fly's salivary glands are able to mount an immune response and what the major characterist  ...[more]

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