Genomics

Dataset Information

59


ABSTRACT: Relationship between nucleosome positioning and DNA methylation

PROVIDER: PRJNA125825 | ENA |

REPOSITORIES: ENA

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Publications


Nucleosomes compact and regulate access to DNA in the nucleus, and are composed of approximately 147 bases of DNA wrapped around a histone octamer. Here we report a genome-wide nucleosome positioning analysis of Arabidopsis thaliana using massively parallel sequencing of mononucleosomes. By combining this data with profiles of DNA methylation at single base resolution, we identified 10-base periodicities in the DNA methylation status of nucleosome-bound DNA and found that nucleosomal DNA was mor  ...[more]

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