Project description:Primary human M1 and M2 macrophages were transfected with different human herpesvirus-derived viral miRNA and the impact on the cellular microRNAs was profiled using microarray. Viral miRNA-mediated impact was assessed on the host cellular microRNA profiles by miRNA microarray analysis. Five different viral miRNA representing 4 different human herpesviruses were overexpressed in M1 and M2 macrophages and the changes in cellular miRNA compared to control mimic were examined. Viral miRNA exhibit unique impact on M1 and M2 miRNA profiles.

2022-05-31 | GSE150146 | GEO

Viral microRNA expression in two nasal NK T cell lymphoma cell lines

Project description:We have used microarray profiling to examine the expression of viral microRNAs (miRNAs) in two independently derived nasal natural killer T cell lymphoma (NKTCL) cell lines, SNK6 and SNT16. The goal of the study was to investigate the role of the viral miRNAs in the genesis and maintenance of NKTCLs.

2011-11-28 | GSE30695 | GEO

Human whole blood samples: disease discordant twins and healthy controls.

Project description:We sought to utilize disease discordant twins and a novel viral-human gene microarray assay using whole human genome microarray in combination with a set of over 6,000 probes, which correspond to the majority of known viral genesrole of shared viral infections and the activation of shared antiviral signaling pathways in the development of SAID

2016-06-20 | GSE74027 | GEO

Involvement of viral miRNA in the regulation of antiviral apoptosis in shrimp

Project description:In this study, the viral miRNAs from white spot syndrome virus (WSSV) were characterized in shrimp in vivo. On the basis of our previous study and small RNA sequencing in this study, a total of 89 putative WSSV miRNAs were identified. As revealed by miRNA microarray analysis, the expressions of viral miRNAs were tissue-specific in vivo.

2014-01-09 | GSE53900 | GEO

Viruses

Project description:Viral Detection Microarray Analysis of Unknown Tropical Febrile Illness Cases

| PRJNA139553 | ENA

Distinct expression pattern of miRNAs in Marek’s disease virus infected-chicken splenic tumors and non-tumorous spleen tissues

Project description:To gain more insight into the molecular mechanisms of the tumorigenesis of MDV, we used microarrays to screen host and viral miRNAs that were sensitive to infection by MDV. Microarray analysis showed significant differential expression of 79 miRNAs,

2014-04-01 | GSE56364 | GEO

T-cells' gene expression after high-dose melphalan

Project description:T-cells' transduction efficacy by lentiviral transduction is diminished after high-dose melphalan. To investigate transcriptional changes regarding genes inhibiting viral entry, reverse transcription, nuclear transport and viral genome integration, we performed microarray transcription analysis.

2020-11-23 | GSE148770 | GEO

An immune response network associated with blood lipid levels

Project description:Genome-wide genotyping was performed on a population-based cohort from the capital region of Finland using the Illumina 610-Quad SNP microarray

| EGAS00000000086 | EGA

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