Genomics

Dataset Information

0

Escherichia coli


ABSTRACT: Bile Salts Influence Virulence Properties of E. coli O157:H7

ORGANISM(S): Escherichia coli  

PROVIDER: PRJNA128967 | ENA |

REPOSITORIES: ENA

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Publications

Bile salts induce resistance to polymyxin in enterohemorrhagic Escherichia coli O157:H7.

Kus Julianne V JV   Gebremedhin Ahferom A   Dang Vica V   Tran Seav-Ly SL   Serbanescu Anca A   Barnett Foster Debora D  

Journal of bacteriology 20110701 17


Many enteric bacteria use bile as an environmental cue to signal resistance and virulence gene expression. Microarray analysis of enterohemorrhagic Escherichia coli O157:H7 (EHEC) treated with bile salts revealed upregulation of genes for an efflux system (acrAB), a two-component signal transduction system (basRS/pmrAB), and lipid A modification (arnBCADTEF and ugd). Bile salt treatment of EHEC produced a basS- and arnT-dependent resistance to polymyxin. ...[more]

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