Genomics

Dataset Information

59

Escherichia coli


ABSTRACT: E. coli K-12 mutant yjgI biofilm vs. wild type biofilm

ORGANISM(S): Escherichia coli  

PROVIDER: PRJNA128971 | ENA |

REPOSITORIES: ENA

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Publications

Engineering a novel c-di-GMP-binding protein for biofilm dispersal.

Ma Qun Q   Yang Zhonghua Z   Pu Mingming M   Peti Wolfgang W   Wood Thomas K TK  

Environmental microbiology 20101108 3


Bacteria prefer to grow attached to themselves or an interface, and it is important for an array of applications to make biofilms disperse. Here we report simultaneously the discovery and protein engineering of BdcA (formerly YjgI) for biofilm dispersal using the universal signal 3,5-cyclic diguanylic acid (c-di-GMP). The bdcA deletion reduced biofilm dispersal, and production of BdcA increased biofilm dispersal to wild-type level. Since BdcA increases motility and extracellular DNA production w  ...[more]

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