Dataset Information


Homo sapiens

ABSTRACT: Gene expression profiling of gastroesophageal adenocarcinoma

ORGANISM(S): Homo sapiens  



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Genetic profiles of gastroesophageal cancer: combined analysis using expression array and tiling array--comparative genomic hybridization.

Isinger-Ekstrand Anna A   Johansson Jan J   Ohlsson Mattias M   Francis Princy P   Staaf Johan J   Jönsson Mats M   Borg Ake A   Nilbert Mef M  

Cancer genetics and cytogenetics 20100701 2

We aimed to characterize the genomic profiles of adenocarcinomas in the gastroesophageal junction in relation to cancers in the esophagus and the stomach. Profiles of gains/losses as well as gene expression profiles were obtained from 27 gastroesophageal adenocarcinomas by means of 32k high-resolution array-based comparative genomic hybridization and 27k oligo gene expression arrays, and putative target genes were validated in an extended series. Adenocarcinomas in the distal esophagus and the g  ...[more]

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