Genomics

Dataset Information

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Genetic architecture of murine skin inflammation and tumor susceptibility


ABSTRACT: Genetic architecture of murine skin inflammation and tumor susceptibility

PROVIDER: PRJNA129003 | ENA |

REPOSITORIES: ENA

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Publications

Identification of Hipk2 as an essential regulator of white fat development.

Sjölund Jonas J   Pelorosso Facundo G FG   Quigley David A DA   DelRosario Reyno R   Balmain Allan A  

Proceedings of the National Academy of Sciences of the United States of America 20140430 20


Homeodomain-interacting protein kinase 2 (Hipk2) has previously been implicated in the control of several transcription factors involved in embryonic development, apoptosis, cell proliferation, and tumor development, but very little is understood about the exact mechanisms through which Hipk2 influences these processes. Analysis of gene expression in normal tissues from genetically heterogeneous mouse or human populations can reveal network motifs associated with the structural or functional com  ...[more]

Publication: 1/2

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