Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: PBMC IFNg Dose Reponse

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA129029 | ENA |

REPOSITORIES: ENA

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Publications

Dissecting interferon-induced transcriptional programs in human peripheral blood cells.

Waddell Simon J SJ   Popper Stephen J SJ   Rubins Kathleen H KH   Griffiths Michael J MJ   Brown Patrick O PO   Levin Michael M   Relman David A DA  

PloS one 20100322 3


Interferons are key modulators of the immune system, and are central to the control of many diseases. The response of immune cells to stimuli in complex populations is the product of direct and indirect effects, and of homotypic and heterotypic cell interactions. Dissecting the global transcriptional profiles of immune cell populations may provide insights into this regulatory interplay. The host transcriptional response may also be useful in discriminating between disease states, and in underst  ...[more]

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