Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Profiling neuroblastoma SH-SY5Y with Paraquat treatment

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA129435 | ENA |

REPOSITORIES: ENA

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Publications


Mitochondrial dysfunction has been implicated in the pathogenesis of a number of neurodegenerative disorders including Parkinson, Alzheimer, and Amyotrophic Lateral Sclerosis (ALS). In addition, aberrant mRNA splicing has been documented in neurodegeneration. To characterize the cellular response to mitochondrial perturbations at the level of gene expression and alternative pre-mRNA splicing we used splicing-sensitive microarrays to profile human neuroblastoma SH-SY5Y cells treated with paraquat  ...[more]

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