Genomics

Dataset Information

0

Caenorhabditis elegans


ABSTRACT: QX recombinant inbred advanced intercross lines of C. elegans

ORGANISM(S): Caenorhabditis elegans  

PROVIDER: PRJNA130633 | ENA |

REPOSITORIES: ENA

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Publications

Selection at linked sites shapes heritable phenotypic variation in C. elegans.

Rockman Matthew V MV   Skrovanek Sonja S SS   Kruglyak Leonid L  

Science (New York, N.Y.) 20101001 6002


Mutation generates the heritable variation that genetic drift and natural selection shape. In classical quantitative genetic models, drift is a function of the effective population size and acts uniformly across traits, whereas mutation and selection act trait-specifically. We identified thousands of quantitative trait loci (QTLs) influencing transcript abundance traits in a cross of two Caenorhabditis elegans strains; although trait-specific mutation and selection explained some of the observed  ...[more]

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