Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Expression profiles from HEK293 cells by overexpression of TRPM7 channel

PROVIDER: PRJNA131859 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

Alteration of the transcriptional profile of human embryonic kidney cells by transient overexpression of mouse TRPM7 channels.

Lee Byoung-Cheol BC   Hong Seong-Eui SE   Lim Hyun-Ho HH   Kim Do Han DH   Park Chul-Seung CS  

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110401 3-4


<h4>Background</h4>TRPM7 is a cation channel containing a functional kinase domain. The functional activity of TRPM7 is essential for cell viability and growth, and its expression is up-regulated in certain pathological conditions, such as ischemia.<h4>Methods</h4>In order to assess the effects of TRPM7 activity on cellular gene expression, inducible HEK293 cell-lines harboring the wild-type mouse TRPM7 and a mutant lacking the kinase domain were established. The wild-type and the non-functional  ...[more]

Similar Datasets

| E-GEOD-23102 | BioStudies
2011-07-23 | GSE23102 | GEO
2011-07-22 | E-GEOD-23102 | ArrayExpress
| S-EPMC2151519 | BioStudies
| S-EPMC7016641 | BioStudies
| S-EPMC4806911 | BioStudies
| S-EPMC7827240 | BioStudies
| S-EPMC6928690 | BioStudies
| S-EPMC2887440 | BioStudies
| S-EPMC8726484 | BioStudies