Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Copy number variation in inbred and wild mice

ABSTRACT: Copy number variation in inbred and wild mice

PROVIDER: PRJNA133505 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Validation and copy number variation in inbred and wild mice

Project description:This SuperSeries is composed of the following subset Series: GSE24424: Copy number variation in inbred and wild mice GSE24640: Validation of a subset of copy number variants from GSE24424 by aCGH Refer to individual Series

2010-12-31 | E-GEOD-24643 | biostudies-arrayexpress

Copy number variation in inbred and wild mice

2010-12-31 | GSE24424 | GEO

Copy number variation in inbred and wild mice

Project description:Copy number variants were determined in 3-5 males from 13 inbred laboratory mouse strains and 21 Mus musculus individuals caught in various geographic locations, using Nimblegen 385k arrays. CopyMap was used to predict CNVs. 3-5 males from 13 inbred strains and 21 Mus musculus caught in various geographic locations were compared to a single C57BL/6J individual by array comparative genome hybridisation.

2010-12-31 | E-GEOD-24424 | biostudies-arrayexpress

Great Ape Copy Number Variation

Project description:Great Ape Copy Number Variation

| PRJNA144461 | ENA

Recurrent DNA copy number variation in the laboratory mouse

Project description:We have conducted a genome-wide analysis of spontaneous copy number variation (CNV) in the laboratory mouse. We used high resolution microarrays to identify 38 CNVs between 14 colonies of the C57BL/6 strain spanning ~967 generations of inbreeding, and examined these loci in 12 additional strains. It is clear from our results that many CNVs arise through a highly non-random process: 18 of 38 were the product of recurrent mutation, and rates of change vary roughly four orders of magnitude across different loci. These recurrent CNVs are distributed throughout the genome, affect 43 genes, and fluctuate in copy number over mere hundreds of generations, observations that raise questions about their contribution to natural variation. Keywords: Representational oligonucleotide microarray analysis, comparative genomic hybridization, DNA copy number variation, structural variation, inbred mice, spontaneous mutation rate

2007-10-28 | GSE8980 | GEO

Recurrent DNA copy number variation in the laboratory mouse

Project description:We have conducted a genome-wide analysis of spontaneous copy number variation (CNV) in the laboratory mouse. We used high resolution microarrays to identify 38 CNVs between 14 colonies of the C57BL/6 strain spanning ~967 generations of inbreeding, and examined these loci in 12 additional strains. It is clear from our results that many CNVs arise through a highly non-random process: 18 of 38 were the product of recurrent mutation, and rates of change vary roughly four orders of magnitude across different loci. These recurrent CNVs are distributed throughout the genome, affect 43 genes, and fluctuate in copy number over mere hundreds of generations, observations that raise questions about their contribution to natural variation. Keywords: comparative genomic hybridization, DNA copy number variation, structural variation, inbred mice, spontaneous mutation rate

2007-10-28 | GSE8885 | GEO

Analyses of copy number variation in domestic and wild pig genomes

Project description:Copy number variation in porcine genomes

| PRJEB667 | ENA

Gene copy number variation profiling by microarray

Project description:Gene copy number variation profiling by microarray

| PRJNA712994 | ENA

Global variation of copy number in the MCF7 genome

Project description:Identify copy number variation in the MCF7 genome Keywords: Copy number variation detection

2008-02-08 | GSE8508 | GEO

Global variation of copy number in the human genome_EA

Project description:Identify and categorize copy number variation in normal populations Keywords: Copy number variation detection