Dataset Information


Bos taurus

ABSTRACT: Gene transcription profiles showing early systemic response to E. coli (k2bh2) infection in bovine liver

ORGANISM(S): Bos taurus  



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Transcriptional profiling of the bovine hepatic response to experimentally induced E. coli mastitis.

Jørgensen Hanne B H HB   Buitenhuis Bart B   Røntved Christine M CM   Jiang Li L   Ingvartsen Klaus L KL   Sørensen Peter P  

Physiological genomics 20120410 11

The mammalian liver works to keep the body in a state of homeostasis and plays an important role in systemic acute phase response to infections. In this study we investigated the bovine hepatic acute phase response at the gene transcription level in dairy cows with experimentally Escherichia coli-induced mastitis. At time = 0, each of 16 periparturient dairy cows received 20-40 colony-forming units of live E. coli in one front quarter of the udder. A time series of liver biopsies was collected a  ...[more]

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