Dataset Information


Mus musculus

ABSTRACT: Expression data from postnatal mouse apical and basal organ of Corti from Dicer1 conditional knockout and littermate control cochleae.

ORGANISM(S): Mus musculus  



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MicroRNA-183 family expression in hair cell development and requirement of microRNAs for hair cell maintenance and survival.

Weston Michael D MD   Pierce Marsha L ML   Jensen-Smith Heather C HC   Fritzsch Bernd B   Rocha-Sanchez Sonia S   Beisel Kirk W KW   Soukup Garrett A GA  

Developmental dynamics : an official publication of the American Association of Anatomists 20110228 4

MicroRNAs (miRNAs) post-transcriptionally repress complementary target gene expression and can contribute to cell differentiation. The coordinate expression of miRNA-183 family members (miR-183, miR-96, and miR-182) has been demonstrated in sensory cells of the mouse inner ear and other vertebrate sensory organs. To further examine hair cell miRNA expression in the mouse inner ear, we have analyzed miR-183 family expression in wild type animals and various mutants with defects in neurosensory de  ...[more]

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