Dataset Information


Mus musculus

ABSTRACT: Altered Gene Expression in Placentae from a Mouse Model of Diabetic Pregnancy

ORGANISM(S): Mus musculus  



altmetric image


Altered gene expression and spongiotrophoblast differentiation in placenta from a mouse model of diabetes in pregnancy.

Salbaum J M JM   Kruger C C   Zhang X X   Delahaye N Arbour NA   Pavlinkova G G   Burk D H DH   Kappen C C  

Diabetologia 20110414 7

<h4>Aims/hypothesis</h4>Pregnancies complicated by diabetes have a higher risk of adverse outcomes for mothers and children, including predisposition to disease later in life, e.g. metabolic syndrome and hypertension. We hypothesised that adverse outcomes from diabetic pregnancies may be linked to compromised placental function, and sought to identify cellular and molecular abnormalities in diabetic placenta.<h4>Methods</h4>Using a mouse model of diabetic pregnancy, placental gene expression was  ...[more]

Similar Datasets

2018-01-01 | S-EPMC6248656 | BioStudies
2011-06-01 | E-GEOD-28277 | ArrayExpress
2011-06-01 | GSE28277 | GEO
1000-01-01 | S-EPMC2571111 | BioStudies
2015-01-01 | S-EPMC4490682 | BioStudies
2008-01-01 | S-EPMC2963627 | BioStudies
2011-01-01 | S-EPMC3882064 | BioStudies
2018-01-01 | S-EPMC5826263 | BioStudies
1000-01-01 | S-EPMC5321798 | BioStudies
2009-01-01 | S-EPMC2644715 | BioStudies