Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Effects of KLF5 overexpression on renal collecting duct epithelial cell line (mIMCD-3)

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA140117 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice.

Fujiu Katsuhito K   Manabe Ichiro I   Nagai Ryozo R  

The Journal of clinical investigation 20110808 9


Renal tubulointerstitial damage is the final common pathway leading from chronic kidney disease to end-stage renal disease. Inflammation is clearly involved in tubulointerstitial injury, but it remains unclear how the inflammatory processes are initiated and regulated. Here, we have shown that in the mouse kidney, the transcription factor Krüppel-like factor-5 (KLF5) is mainly expressed in collecting duct epithelial cells and that Klf5 haploinsufficient mice (Klf5+/- mice) exhibit ameliorated re  ...[more]

Similar Datasets

2011-05-17 | E-GEOD-29323 | ArrayExpress
| PRJNA437290 | ENA
2013-11-19 | E-GEOD-52448 | ArrayExpress
| GSE95008 | GEO
2010-12-09 | GSE19938 | GEO
2010-12-09 | E-GEOD-19938 | ArrayExpress
2013-08-08 | E-GEOD-49616 | ArrayExpress
2018-10-26 | PXD005488 | Pride
| PRJNA87623 | ENA
| PRJNA92439 | ENA