Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Global gene expression profiles of iPSC from SMA patient, unaffected father and iPS 19.9 compared to transcriptomic data obtained by corresponding fibroblasts

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA141985 | ENA |

REPOSITORIES: ENA

altmetric image

Publications


Spinal muscular atrophy (SMA) is among the most common genetic neurological diseases that cause infant mortality. Induced pluripotent stem cells (iPSCs) generated from skin fibroblasts from SMA patients and genetically corrected have been proposed to be useful for autologous cell therapy. We generated iPSCs from SMA patients (SMA-iPSCs) using nonviral, nonintegrating episomal vectors and used a targeted gene correction approach based on single-stranded oligonucleotides to convert the survival mo  ...[more]

Similar Datasets

| GSE27206 | GEO
2013-01-04 | E-GEOD-27206 | ArrayExpress
2013-01-04 | E-GEOD-27205 | ArrayExpress
| GSE13828 | GEO
2009-01-13 | E-GEOD-13828 | ArrayExpress
| GSE61390 | GEO
| PRJNA141983 | ENA
| GSE104499 | GEO
2012-10-17 | E-GEOD-33298 | ArrayExpress
2018-12-31 | E-MTAB-4964 | ArrayExpress