Genomics

Dataset Information

59

Homo sapiens


ABSTRACT: Gene expression profiling of primary acute lymphoblastic leukemia (ALL) cells

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA142009 | ENA |

REPOSITORIES: ENA

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Publications


We determined the genome-wide digital gene expression (DGE) profiles of primary acute lymphoblastic leukemia (ALL) cells from 21 patients taking advantage of 'second-generation' sequencing technology. Patients included in this study represent four cytogenetically distinct subtypes of B-cell precursor (BCP) ALL and T-cell lineage ALL (T-ALL). The robustness of DGE combined with supervised classification by nearest shrunken centroids (NSC) was validated experimentally and by comparison with publis  ...[more]

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