Genomics

Dataset Information

824

Ascaris suum


ABSTRACT: Ascaris suum transcriptome (RNA-Seq) data

ORGANISM(S): Ascaris suum  

PROVIDER: PRJNA142041 | ENA |

REPOSITORIES: ENA

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Publications

Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles.

Wang Jianbin J   Czech Benjamin B   Crunk Amanda A   Wallace Adam A   Mitreva Makedonka M   Hannon Gregory J GJ   Davis Richard E RE  

Genome research 20110617 9


Eukaryotic cells express several classes of small RNAs that regulate gene expression and ensure genome maintenance. Endogenous siRNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs) mainly control gene and transposon expression in the germline, while microRNAs (miRNAs) generally function in post-transcriptional gene silencing in both somatic and germline cells. To provide an evolutionary and developmental perspective on small RNA pathways in nematodes, we identified and characterized known and  ...[more]

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