Genomics

Dataset Information

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Rattus norvegicus


ABSTRACT: Rat model of MTLE: Animals with epilepsy vs animals without epilepsy (codelink)

ORGANISM(S): Rattus norvegicus  

PROVIDER: PRJNA142077 | ENA |

REPOSITORIES: ENA

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Publications


Neither the molecular basis of the pathologic tendency of neuronal circuits to generate spontaneous seizures (epileptogenicity) nor anti-epileptogenic mechanisms that maintain a seizure-free state are well understood. Here, we performed transcriptomic analysis in the intrahippocampal kainate model of temporal lobe epilepsy in rats using both Agilent and Codelink microarray platforms to characterize the epileptic processes. The experimental design allowed subtraction of the confounding effects of  ...[more]

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