Dataset Information


Sus scrofa

ABSTRACT: Comparative transcriptomic profiling of peripheral blood mononuclear cells (PBMNCs) isolated from pigs exposed to an atherogenic diet (AD) or to an AD supplemented with Grape Extract (GE) and/or Resveratrol (RES).

ORGANISM(S): Sus scrofa  



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A dietary resveratrol-rich grape extract prevents the developing of atherosclerotic lesions in the aorta of pigs fed an atherogenic diet.

Azorín-Ortuño María M   Yañéz-Gascón María Josefa MJ   Pallarés Francisco J FJ   Rivera José J   González-Sarrías Antonio A   Larrosa Mar M   Vallejo Fernando F   García-Conesa María Teresa MT   Tomás-Barberán Francisco F   Espín Juan Carlos JC  

Journal of agricultural and food chemistry 20120524 22

The presence of grape and wine polyphenol resveratrol (RES) in the diet is negligible. Therefore, the cardiovascular benefits of this molecule, in a dietary context, remain to be established. We aimed to investigate, through dietary intervention, the effects of a resveratrol-rich grape extract (GE-RES) on the prevention of early aortic lesions in pigs fed an atherogenic diet (AD). These effects were compared with those produced by a grape extract lacking RES (GE) or RES alone. Pigs fed the AD fo  ...[more]

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