Genomics

Dataset Information

25

Mus musculus


ABSTRACT: Expression data from sorted Id3-GFP hi Id2-YFP int and Id3-GFP lo Id2-YFP hi activated CD8 T cells

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA147035 | ENA |

REPOSITORIES: ENA

altmetric image

Publications


During infection, naive CD8(+) T cells differentiate into effector cells, which are armed to eliminate pathogens, and memory cells, which are poised to protect against reinfection. The transcriptional program that regulates terminal differentiation into short-lived effector-memory versus long-lived memory cells is not clearly defined. Through the use of mice expressing reporters for the DNA-binding inhibitors Id2 and Id3, we identified Id3(hi) precursors of long-lived memory cells before the pea  ...[more]

Similar Datasets

2011-10-06 | E-GEOD-32675 | ArrayExpress
2011-10-07 | GSE32675 | GEO
2011-01-01 | S-EPMC3872000 | BioStudies
2013-01-01 | S-EPMC3563862 | BioStudies
2009-01-01 | S-EPMC2802685 | BioStudies
2011-01-01 | S-EPMC3159403 | BioStudies
1000-01-01 | S-EPMC2118360 | BioStudies
2009-01-01 | S-EPMC2706276 | BioStudies
1000-01-01 | S-EPMC1567699 | BioStudies
2016-01-01 | S-EPMC4828702 | BioStudies