Genomics

Dataset Information

0

Mus musculus


ABSTRACT: A Wnt-Bmp feedback circuit controls inter-tissue signaling dynamics in tooth organogenesis

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA147281 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

A Wnt-bmp feedback circuit controls intertissue signaling dynamics in tooth organogenesis.

O'Connell Daniel J DJ   Ho Joshua W K JW   Mammoto Tadanori T   Turbe-Doan Annick A   O'Connell Joyce T JT   Haseley Psalm S PS   Koo Samuel S   Kamiya Nobuhiro N   Ingber Donald E DE   Park Peter J PJ   Maas Richard L RL  

Science signaling 20120110 206


Many vertebrate organs form through the sequential and reciprocal exchange of signaling molecules between juxtaposed epithelial and mesenchymal tissues. We undertook a systems biology approach that combined the generation and analysis of large-scale spatiotemporal gene expression data with mouse genetic experiments to gain insight into the mechanisms that control epithelial-mesenchymal signaling interactions in the developing mouse molar tooth. We showed that the shift in instructive signaling p  ...[more]

Similar Datasets

| GSE80288 | GEO
| GSE81282 | GEO
2019-03-21 | BIOMD0000000648 | BioModels
2019-08-09 | BIOMD0000000656 | BioModels
2019-08-21 | BIOMD0000000654 | BioModels
2019-08-21 | BIOMD0000000655 | BioModels
2019-03-21 | BIOMD0000000652 | BioModels
2019-03-21 | BIOMD0000000653 | BioModels
| GSE87653 | GEO
| GSE87652 | GEO