Genomics,Multiomics

Dataset Information

0

Homo sapiens


ABSTRACT: Analysis of miRNA profiles in CD4+ T-lymphocytes following exposure to HIV-1

OTHER RELATED OMICS DATASETS IN: E-GEOD-33514

PROVIDER: PRJNA148815 | ENA |

REPOSITORIES: ENA

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Publications


MicroRNAs (miRNAs) inhibit HIV-1 expression by either modulating host innate immunity or by directly interfering with viral mRNAs. We evaluated the expression of 377 miRNAs in CD4(+) T cells from HIV-1 élite long-term nonprogressors (éLTNPs), naive patients, and multiply exposed uninfected (MEU) patients, and we observed that the éLTNP patients clustered with naive patients, whereas all MEU subjects grouped together. The discriminatory power of miRNAs showed that 21 miRNAs significantly differen  ...[more]

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