Genomics

Dataset Information

176

Arabidopsis thaliana


ABSTRACT: Whole genome bisulfite sequencing of idm1, rdd, ros1 mutants and Col-0 WT

ORGANISM(S): Arabidopsis thaliana  

PROVIDER: PRJNA149493 | ENA |

REPOSITORIES: ENA

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Publications


Active DNA demethylation is an important part of epigenetic regulation in plants and animals. How active DNA demethylation is regulated and its relationship with histone modification patterns are unclear. Here, we report the discovery of IDM1, a regulator of DNA demethylation in Arabidopsis. IDM1 is required for preventing DNA hypermethylation of highly homologous multicopy genes and other repetitive sequences that are normally targeted for active DNA demethylation by Repressor of Silencing 1 an  ...[more]

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