Genomics

Dataset Information

0


ABSTRACT: Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant

PROVIDER: PRJNA150773 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile.

Antunes Ana A   Camiade Emilie E   Monot Marc M   Courtois Emmanuelle E   Barbut Frédéric F   Sernova Natalia V NV   Rodionov Dmitry A DA   Martin-Verstraete Isabelle I   Dupuy Bruno B  

Nucleic acids research 20120918 21


The catabolite control protein CcpA is a pleiotropic regulator that mediates the global transcriptional response to rapidly catabolizable carbohydrates, like glucose in Gram-positive bacteria. By whole transcriptome analyses, we characterized glucose-dependent and CcpA-dependent gene regulation in Clostridium difficile. About 18% of all C. difficile genes are regulated by glucose, for which 50% depend on CcpA for regulation. The CcpA regulon comprises genes involved in sugar uptake, fermentation  ...[more]

Similar Datasets

2012-10-02 | E-GEOD-35152 | ArrayExpress
2012-10-02 | E-GEOD-35071 | ArrayExpress
2012-10-02 | E-GEOD-35070 | ArrayExpress
2012-11-13 | E-GEOD-34971 | ArrayExpress
| PRJNA156171 | ENA
| PRJNA156169 | ENA
| GSE35073 | GEO
2011-08-21 | E-GEOD-25521 | ArrayExpress
2012-10-02 | E-GEOD-35073 | ArrayExpress
| GSE42471 | GEO