Genomics

Dataset Information

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Bacillus subtilis


ABSTRACT: High- and low-affinity cre boxes for CcpA binding in Bacillus subtilis revealed by genome-wide analysis

ORGANISM(S): Bacillus subtilis  

PROVIDER: PRJNA150777 | ENA |

REPOSITORIES: ENA

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Publications

High- and low-affinity cre boxes for CcpA binding in Bacillus subtilis revealed by genome-wide analysis.

Marciniak Bogumiła C BC   Pabijaniak Monika M   de Jong Anne A   Dűhring Robert R   Seidel Gerald G   Hillen Wolfgang W   Kuipers Oscar P OP  

BMC genomics 20120817


BACKGROUND: In Bacillus subtilis and its relatives carbon catabolite control, a mechanism enabling to reach maximal efficiency of carbon and energy sources metabolism, is achieved by the global regulator CcpA (carbon catabolite protein A). CcpA in a complex with HPr-Ser-P (seryl-phosphorylated form of histidine-containing protein, HPr) binds to operator sites called catabolite responsive elements, cre. Depending on the cre box position relative to the promoter, the CcpA/HPr-Ser-P complex can eit  ...[more]

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