Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Gene expression profiling of human Th17 cell differentiation

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA150893 | ENA |

REPOSITORIES: ENA

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Publications


Th17 cells play an essential role in the pathogenesis of autoimmune and inflammatory diseases. Most of our current understanding on Th17 cell differentiation relies on studies carried out in mice, whereas the molecular mechanisms controlling human Th17 cell differentiation are less well defined. In this study, we identified gene expression changes characterizing early stages of human Th17 cell differentiation through genome-wide gene expression profiling. CD4(+) cells isolated from umbilical cor  ...[more]

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