Project description:This SuperSeries is composed of the following subset Series: GSE30758: Epigenome analysis of normal cells from the uterine cervix in a nested prospective case control study within the ARTISTIC trial GSE30759: Epigenome analysis of normal and cancer tissue from the uterine cervix Refer to individual Series
Project description:The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs in normal and cancer tissue from the uterine cervix. There are a total of 63 samples, 15 samples of normal histology and 48 cervical cancers. The normal cervical samples were from women who underwent a hysterectomy for uterine fibroids. The 48 cervical cancers were from women who were treated at the Innsbruck Medical University between 1990 and 2006.
Project description:We identified an altered miRNA expression in adenocarcinoma of the uterine cervix compared with normal cervix and futhermore analyzed their association with clinicopthologic characteristics.
