Genomics

Dataset Information

59

Homo sapiens


ABSTRACT: All exon array expression data in normal colon and primary colon cancer lines [expression]

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA155553 | ENA |

REPOSITORIES: ENA

altmetric image

Publications


Cancer is characterized by gene expression aberrations. Studies have largely focused on coding sequences and promoters, even though distal regulatory elements play a central role in controlling transcription patterns. We used the histone mark H3K4me1 to analyze gain and loss of enhancer activity genome-wide in primary colon cancer lines relative to normal colon crypts. We identified thousands of variant enhancer loci (VELs) that comprise a signature that is robustly predictive of the in vivo col  ...[more]

Similar Datasets

2012-04-15 | E-GEOD-36401 | ArrayExpress
2012-04-15 | E-GEOD-36400 | ArrayExpress
2015-05-02 | E-GEOD-68468 | ArrayExpress
2012-04-15 | E-GEOD-36204 | ArrayExpress
| PRJNA186750 | ENA
2015-11-21 | E-GEOD-75205 | ArrayExpress
2010-07-07 | E-GEOD-14297 | ArrayExpress
| PRJNA142243 | ENA
2010-07-07 | GSE14297 | GEO
| GSE75500 | GEO