Genomics

Dataset Information

118

Homo sapiens


ABSTRACT: HNRPA2B1 HITS-CLIP

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA155915 | ENA |

REPOSITORIES: ENA

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Publications

Systematic discovery of structural elements governing stability of mammalian messenger RNAs.

Goodarzi Hani H   Najafabadi Hamed S HS   Oikonomou Panos P   Greco Todd M TM   Fish Lisa L   Salavati Reza R   Cristea Ileana M IM   Tavazoie Saeed S  

Nature 20120408 7397


Decoding post-transcriptional regulatory programs in RNA is a critical step towards the larger goal of developing predictive dynamical models of cellular behaviour. Despite recent efforts, the vast landscape of RNA regulatory elements remains largely uncharacterized. A long-standing obstacle is the contribution of local RNA secondary structure to the definition of interaction partners in a variety of regulatory contexts, including--but not limited to--transcript stability, alternative splicing a  ...[more]

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